Indications and Usage
XEOMIN® (incobotulinumtoxinA) for injection, and for intramuscular use, is a prescription medication that is injected into facial muscles for the temporary improvement in the appearance of moderate to severe glabellar lines (frown lines) in adult patients.
XEOMIN® should be administered no more frequently than every three months.
IMPORTANT SAFETY INFORMATION
WARNING: DISTANT SPREAD OF TOXIN EFFECT
The effects of XEOMIN® (incobotulinumtoxinA) for injection, for intramuscular use, and all botulinum toxin products may spread from the area of injection and produce effects that include loss of strength, muscle weakness all over the body, double vision, blurred vision, drooping eyelids, trouble swallowing, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, and trouble breathing. These symptoms have been reported hours to weeks after injection. Swallowing and breathing difficulties can be life threatening and there have been reports of death. The risk of symptoms is probably greatest in children treated for spasticity but symptoms can also occur in adults, particularly in those patients who have underlying conditions that would predispose them to these symptoms. Cases in which the effect has spread have occurred both at the doses used for the treatment of neck spasticity and disorders of muscle tone and at lower doses.